Medicine

Now that France has approved Hydroxychloroquine after Prof Raoult’s second test, it is helpful to go back and roll the tape. We need to understand why we are where we are now, over a month after China — which, unsurprisingly, did a lot of the early work on Covid-19 that we are all relying on now — published information on promising drugs. Here is Clinical Trials Arena, February 18th: 18 February 2020 News Coronavirus: Chloroquine yields positive data in Covid-19 trial Early data from clinical trials being performed in China has revealed that chloroquine phosphate could help treat the new coronavirus disease, Covid-19. China National Center for Biotechnology Development deputy head Sun Yanrong said that chloroquine, an anti-malarial medication, was Read More ›

France 24, English has the vid: This is a breakthrough of hope for those who may fall victim to the disease. HT, Vivid. I link the Daily Wire report Vivid links, given the onward confirmation: France Officially Sanctions Drug After 78 Of 80 Patients Recover From COVID-19 Within Five Days By  Amanda PrestigiacomoDailyWire.com The French government has officially sanctioned chloroquine, a drug often used to fight malaria, for certain patients infected with the novel coronavirus, or COVID-19. “The French government has officially sanctioned prescriptions of chloroquine to treat certain coronavirus patients,” France 24 English reported Saturday. “This ensures continued treatment of patients who have been treated for several years for a chronic condition with this drug, but also allows a Read More ›

BREAKING: Professor Raoult has released a further result. Using Google Translate on two tweets: Our two articles published this evening help to demonstrate:      1. The effectiveness of our protocol, on 80 patients.      2. The relevance of the association of hydroxychloroquine and azithromycin, thanks to research carried out in our P3 containment laboratory. https://t.co/Y91bsFOgB2      – Didier Raoult (@raoult_didier) March 27, 2020 and: New article published online by my teams: in vitro demonstration of the hydroxychloroquine / azithromycin synergy to counter the replication of SARS-COV2      In vitro testing of Hydroxychloroquine and Azithromycin on SARS-CoV-2 shows synergistic effecthttps: //t.co/KUaag6N5FF      – Didier Raoult (@raoult_didier) March 27, 2020 Here is a chart in one of the Twitter threads, which seems Read More ›

Here we go: I am an ER MD in New Orleans. Class of 98. Every one of my colleagues have now seen several hundred Covid 19 patients and this is what I think I know. Clinical course is predictable. 2-11 days after exposure (day 5 on average) flu like symptoms start. Common are fever, headache, dry cough, myalgias(back pain), nausea without vomiting, abdominal discomfort with some diarrhea, loss of smell, anorexia, fatigue. Day 5 of symptoms- increased SOB, and bilateral viral pneumonia from direct viral damage to lung parenchyma. Day 10- Cytokine storm leading to acute ARDS and multiorgan failure. You can literally watch it happen in a matter of hours. 81% mild symptoms, 14% severe symptoms requiring hospitalization, 5% Read More ›

Fresh developments, even as in a now all too familiar development, a politically incorrect video vanishes from YouTube. The Boris Johnson case shows just how contagious this virus is, as he joins a list of leading politicians and members of their families. We definitely need a good treatment and we need it fast. In that light, let us see what is being picked up from Belgium: Belgium’s Federal Agency for Medicines and Health Products (FAMHP) is reserving hydroxychloroquine, an anti-malarial drug, for patients who really need it in light of the new coronavirus (Covid-19). The drug, marketed under the name Plaquenil, has entered clinical trials in France and the United States, and its results against Covid-19 are promising, according to Read More ›

First, Dr Vladimir Zelenko speaks: While, the Governor blocks: Sisolak signed an emergency order earlier Tuesday barring the use of anti-malaria drugs for someone who has the coronavirus. But Sisolak’s order does not apply to patients who are hospitalized with coronavirus. The order restricting chloroquine and hydroxychloroquine came after President Donald Trump touted the medication as a treatment and falsely stated that the Food and Drug Administration had just approved the use of chloroquine to treat patients infected with coronavirus. Sisolak said in a statement that there’s no consensus among experts or Nevada doctors that the drugs can treat people with COVID-19. Actually, as Pharmacy Times reported, Thu March 19: Pharmacy Times FDA Announces Two Drugs Given ‘Compassionate Use’ Status Read More ›

UK’s Daily Mail reports: They also provide a map: A concern is that mild cases are masked under the common cold, and that the incubation period may be up to four weeks or thereabouts, not the fortnight that has been used hitherto. They are not finding a “patient zero” for some of these outbreaks, which is why there is talk of un-traceability and climbing towards pandemic. On the design front there is speculation that the genome has traces of engineering, and that people may have not been incinerating animals in a biological lab near Wuhan, but illegally disposing of them in the bush meat trade. Speculation, not confirmation. It will be interesting to see the criteria by which they might Read More ›